Anti-AgingLongevitySleepTelomeres

Epithalamin

What is Epithalamin?

Epithalamin is a natural polypeptide extract from the bovine pineal gland, representing the "Gold Standard" of Khavinson bioregulators. It regulates the entire neuroendocrine system and exhibits profound anti-aging effects. Epithalamin increases telomerase activity (the enzyme that maintains and rebuilds telomere length), directly elongates telomeres in cells, and normalizes melatonin and cortisol secretion patterns. It modulates immune function, activates cell survival pathways, and has been shown in animal studies to extend lifespan by up to 25-40%. Some human clinical trials in Russia suggest reduced overall and cardiovascular mortality. Epithalamin works by restoring the function of the pineal gland, which acts as the body's biological clock and regulates circadian rhythms, reproductive aging, and systemic homeostasis.

Mechanism of Action

Increases telomerase activity via activation of the TERT gene, elongates telomeres in somatic cells, normalizes melatonin and cortisol secretion through pineal gland regulation, modulates immune responses (particularly T-cell function), and promotes chromatin condensation for genetic stability.

Benefits

  • Extends lifespan and delays cellular aging (proven in animal models)
  • Restores circadian rhythms and improves sleep quality
  • Delays reproductive aging in both men and women
  • Potent antioxidant with immune-modulating effects

Clinical Applications

Premature agingCancer preventionMenopauseInsomniaTelomere-related disorders

Typical Dosage

  • 10mg intramuscularly for 10 days (total 100mg per course)

Side Effects

While generally considered safe when used correctly, potential side effects should be monitored. Discontinue use if adverse reactions occur.

Synergistic Combinations

HomeLibraryResearchFavoritesToolsVisuals