CJC-1295

CJC-1295 is a synthetic analogue of Growth Hormone Releasing Hormone (GHRH) that significantly increases plasma growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels. It comes in two forms: with DAC (Drug Affinity Complex) for an extended half-life (6-8 days) and without DAC (often called Modified GRF 1-29) with a short half-life (~30 mins). CJC-1295 works by binding to GHRH receptors in the pituitary, stimulating pulsatile GH release. It is favored for its ability to boost GH levels without significantly elevating prolactin or cortisol. Users often report improved sleep, better skin, and increased lean muscle mass.

For CJC-1295 No DAC (Mod GRF 1-29): Administer 100 mcg subcutaneously 1–3 times daily. Best taken on an empty stomach (1 hour before or 2 hours after meals) to avoid insulin blunting the GH spike. Common times are morning, post-workout, and before bed. Often stacked with Ipamorelin. For CJC-1295 DAC: Administer 1–2 mg once weekly due to its long half-life, though this form is less physiological as it creates a constant GH bleed rather than natural pulses.