Epithalon (Epitalon)

Epithalon (also spelled Epitalon) is a synthetic tetrapeptide that has been extensively researched for its potential anti-aging and longevity benefits. It is believed to work primarily through telomerase activation, which may help preserve or extend telomere length—the protective caps on chromosomes that naturally shorten with age. The peptide also influences the pineal gland, supporting healthy melatonin secretion and circadian rhythm regulation. Research suggests Epithalon may have effects on antioxidant defense, immune modulation, and overall cellular health. While most studies have been conducted in Russia, the peptide has gained international interest for its potential to support healthy aging processes.

Epithalon is administered via subcutaneous or intramuscular injection using well-established research protocols. The two primary approaches are: (1) 'Russian Protocol' — 10 mg daily for 10 consecutive days (total 100 mg), or (2) 'Ukrainian Protocol' — 10 mg once every 4 days for a total of 5 injections over ~17 days (total 50 mg). Cycles are typically repeated every 4–6 months. Each 10 mg vial is reconstituted with 1 mL bacteriostatic water to create a 10 mg/mL solution, making dosing straightforward (100 units = full vial). The peptide may be injected at any consistent time of day, with flexibility in injection timing.