Vialinin A

Vialinin A is a naturally occurring compound, not typically classified as a peptide in the same way as the others listed, but rather a dimeric terphenylquinone isolated from the mushroom *Tylopilus vialii*. It is known for its potent anti-inflammatory properties. Vialinin A works by inhibiting the pro-inflammatory enzyme 12-lipoxygenase (12-LOX) and also by suppressing the activation of NF-κB, a key transcription factor involved in inflammatory responses. By inhibiting these pathways, Vialinin A reduces the production of inflammatory mediators. Research suggests it may have potential therapeutic applications in inflammatory conditions, although it is less commonly discussed in the context of peptide therapies and more in natural product chemistry and pharmacology.