Geroprotective effect of thymalin and epithalamin
Khavinson V.Kh., Morozov V.G.
St. Petersburg Institute of Bioregulation and Gerontology
Advances in Gerontology (Uspekhi Gerontologii) 10: 74-84
Abstract
Article in Russian. Clinical follow-up of 266 older adults for 6-8 years, with Thymalin and/or Epithalamin given during the first 2-3 years. The authors report lower acute respiratory illness and lower mortality than controls (2.0-2.1-fold with Thymalin, 1.6-1.8-fold with Epithalamin, 2.5-fold with both; 4.1-fold with annual treatment for 6 years). Same cohort as PMID 14523363; not randomized or placebo-controlled. Summary based on the PubMed abstract (PMID 12577695).
What the study did
Article in Russian. Clinical follow-up of 266 older adults for 6-8 years, with Thymalin and/or Epithalamin given during the first 2-3 years. The authors report lower acute respiratory illness and lower mortality than controls (2.0-2.1-fold with Thymalin, 1.6-1.8-fold with Epithalamin, 2.5-fold with both; 4.1-fold with annual treatment for 6 years). Same cohort as PMID 14523363; not randomized or placebo-controlled.
Reading it honestly
This summary is based on the PubMed abstract (PMID 12577695). It describes research on the named preparation, not on any capsule product sold today, and it is not a claim that any product treats or prevents a disease.
Looking for oral pineal and thymus bioregulators?
Neither Epithalamin nor Thymalin (both injectable extracts) is sold by Vita-Stream, our affiliate partner. The closest oral products it carries are Endoluten (A-8), a pineal-gland bioregulator, and Thymusol, Vita's US-made thymus bioregulator. This study tested neither, so treat them as related products, not the ones studied.
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Study Limitations
- •Summary based on the PubMed abstract only
- •Single research group; independent replication is limited
- •Results concern the studied preparation, not any capsule product
Key Findings
- ✓Lower reported mortality in treated groups
- ✓Duplicate publication of one cohort
- ✓Single research group
Mechanism of Action
Not studied.