Peptide Epitalon activates chromatin at the old age
Khavinson V.Kh., Lezhava T.A., Monaselidze J.R., Jokhadze T.A., Dvalishvili N.A., Bablishvili N.K., Trofimova S.V.
St. Petersburg Institute of Bioregulation and Gerontology
Neuro Endocrinology Letters 24(5): 329-333
Abstract
Cultured lymphocytes from people aged 76-80 were exposed to synthetic Epitalon. The authors report activation of ribosomal genes, decondensation of pericentromeric structural heterochromatin and release of genes repressed by age-related chromatin condensation. Summary based on the PubMed abstract (PMID 14647006).
What the study did
Cultured lymphocytes from people aged 76-80 were exposed to synthetic Epitalon. The authors report activation of ribosomal genes, decondensation of pericentromeric structural heterochromatin and release of genes repressed by age-related chromatin condensation.
Reading it honestly
This summary is based on the PubMed abstract (PMID 14647006). It describes research on the named preparation, not on any capsule product sold today, and it is not a claim that any product treats or prevents a disease.
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Study Limitations
- •Summary based on the PubMed abstract only
- •Single research group; independent replication is limited
- •Results concern the studied preparation, not any capsule product
Key Findings
- ✓Chromatin activation in aged cells
- ✓Ribosomal gene activity increased
- ✓In vitro only
Mechanism of Action
Proposed by the authors: modification of heterochromatin structure in aged cells.