Metabolic•Research Use Only

MOTS-c

MOTS-c is a mitochondrial-derived peptide (MDP) that regulates metabolic homeostasis. It has been described as an "exercise mimetic" due to its ability to enhance glucose metabolism and physical performance.

Mechanism of Action

It translocates to the nucleus to regulate gene expression related to stress resistance and metabolism. It activates the folate-methionine cycle and AMPK pathway, promoting glucose uptake and fatty acid oxidation.

Key Benefits

Enhances insulin sensitivity
Promotes weight loss
Increases physical endurance
Mitochondrial biogenesis
Anti-aging metabolic effects

Research Protocol

Maintenance
5-10mg weekly
Often dosed as 5mg once a week or 2-3 times a week. Can be painful to inject.

Chemical Properties

FormulaC101H152N28O22S2
Mol. Weight2174.6 g/mol

Side Effects & Risks

  • •Injection site pain (common)
  • •Potential for hypoglycemia
  • •Nausea

Amino Acid Sequence

Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
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