Epithalamin
Эпиталамин
Target Organ
Pineal Gland
Description
Epithalamin is a natural polypeptide extract from the bovine pineal gland, representing the "Gold Standard" of Khavinson bioregulators. It regulates the entire neuroendocrine system and exhibits profound anti-aging effects. Epithalamin increases telomerase activity (the enzyme that maintains and rebuilds telomere length), directly elongates telomeres in cells, and normalizes melatonin and cortisol secretion patterns. It modulates immune function, activates cell survival pathways, and has been shown in animal studies to extend lifespan by up to 25-40%. Some human clinical trials in Russia suggest reduced overall and cardiovascular mortality. Epithalamin works by restoring the function of the pineal gland, which acts as the body's biological clock and regulates circadian rhythms, reproductive aging, and systemic homeostasis.
⚙️ Mechanism of Action
Increases telomerase activity via activation of the TERT gene, elongates telomeres in somatic cells, normalizes melatonin and cortisol secretion through pineal gland regulation, modulates immune responses (particularly T-cell function), and promotes chromatin condensation for genetic stability.
✓ Primary Benefits
- ·Extends lifespan and delays cellular aging (proven in animal models)
- ·Restores circadian rhythms and improves sleep quality
- ·Delays reproductive aging in both men and women
- ·Potent antioxidant with immune-modulating effects
💊Dosing Protocol
Standard Course
10mg intramuscularly for 10 days (total 100mg per course)
Intensive Course
Repeat every 6 months; some protocols use 50mg total in 5–10mg doses
🏥Clinical Applications
Synergistic Stacks
Scientific Validation
Peptide Bioregulators in the Rehabilitation of Cosmonauts
Longitudinal study on cosmonauts demonstrating the efficacy of Epithalamin and Thymalin in restoring immune function and circadian rhythms.
Enhancement of Stress Resistance in Elite Rhythmic Gymnasts
Study with the Russian National Team showing improved recovery and performance using peptide bioregulators.
Geroprotective Effect of Peptides in Gazprom Workers
Large-scale study on 11,000+ workers showing reduced mortality and morbidity.