The Khavinson Catalog21+ Bioregulators
The complete inventory of original Russian peptide bioregulators. Filter by body system, type, or health goal.
Cortexin
Кортексин
Cortexin is a complex of water-soluble polypeptide fractions extracted from the cerebral cortex of young cattle, with molecular weights ranging from 1,000 to 10,000 Daltons. These low-molecular-weight neuropeptides are capable of crossing the blood-brain barrier and exerting tissue-specific effects on the cerebral cortex. The peptide complex modulates neuronal metabolism, regulates neurotransmitter balance (particularly serotonin, dopamine, and amino acids), and restores bioelectrical activity in the brain. Cortexin has been extensively studied in Russia for over 20 years and is used clinically for various neurological and neurodevelopmental conditions.
Cerluten
Церлутен
Cerluten is a natural peptide bioregulator extracted from the cerebral cortex of young animals, containing tissue-specific, low-molecular-weight peptides that support comprehensive brain and central nervous system function. Once absorbed, these peptides interact with specific regions of neuronal DNA, acting as epigenetic switches that activate genes responsible for brain repair, protein synthesis, and cellular regeneration. Cerluten enhances metabolic efficiency within brain tissue, provides antioxidant protection against oxidative damage (particularly critical for the brain), regulates peroxide oxidation, and supports microcirculation to ensure neurons receive adequate oxygen and nutrients. It has been shown to improve synaptic plasticity, neurotransmitter regulation, and overall CNS resilience.
Pinealon
Пинеалон
Pinealon is a synthetic tripeptide bioregulator composed of Glutamic Acid, Aspartic Acid, and Arginine (Glu-Asp-Arg), also known as EDR peptide. Originally studied in Russia and derived from or inspired by pineal gland tissue extracts, Pinealon is designed to optimize pineal gland and overall brain function. Due to its small molecular size, it penetrates cellular and nuclear membranes to directly interact with DNA, modulating gene expression and protein synthesis in neurons. It enhances pineal gland activity (including melatonin production), optimizes neurotransmitter function (serotonin, dopamine, GABA, acetylcholine), provides comprehensive neuroprotection by reducing oxidative stress and supporting mitochondrial function, and influences the MAPK/ERK signaling pathway. Pinealon is recognized as a powerful nootropic with applications in cognitive enhancement and age-related neuroprotection.
Epithalamin
Эпиталамин
Epithalamin is a natural polypeptide extract from the bovine pineal gland, representing the "Gold Standard" of Khavinson bioregulators. It regulates the entire neuroendocrine system and exhibits profound anti-aging effects. Epithalamin increases telomerase activity (the enzyme that maintains and rebuilds telomere length), directly elongates telomeres in cells, and normalizes melatonin and cortisol secretion patterns. It modulates immune function, activates cell survival pathways, and has been shown in animal studies to extend lifespan by up to 25-40%. Some human clinical trials in Russia suggest reduced overall and cardiovascular mortality. Epithalamin works by restoring the function of the pineal gland, which acts as the body's biological clock and regulates circadian rhythms, reproductive aging, and systemic homeostasis.
Endoluten
Эндолутен
Endoluten is a natural peptide bioregulator extracted from the pineal gland of young animals, representing the oral equivalent of Epithalamin (the injectable gold standard). It contains peptide complex A-8, consisting of low-molecular-weight peptides with tissue-specific action on the pineal gland. Endoluten works by supporting the pineal gland's natural production of melatonin and other regulatory hormones, rather than supplying melatonin exogenously. It normalizes all cyclic processes in the body—including sleep-wake cycles, hormonal balance, reproductive function, and immune regulation. Due to its potency, Endoluten is typically taken less frequently than other bioregulators (e.g., every 3 days). It is recommended for systemic bioregulation, cancer risk reduction, electromagnetic stress mitigation, and overall longevity support.
Epitalon
Эпиталон
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) that is the active component of Epithalamin, confirmed to exist endogenously in pineal gland extracts in 2017. It is the most researched synthetic anti-aging peptide in the world. Epitalon activates the telomerase enzyme by inducing expression of TERT gene components, leading to telomere elongation at the ends of chromosomes—the protective caps that shorten with each cell division and contribute to cellular aging. Studies show it can increase telomere length by an average of 33%, though results vary among individuals. Epitalon also regulates melatonin synthesis via pineal gland support, improving sleep and hormonal balance. It has antioxidant properties, enhances immune function, and may reduce the risk of age-related neurodegenerative diseases.
Thyreogen
Тиреоген
Natural peptide complex from the thyroid gland. Normalizes thyroid function regardless of hypo- or hyperthyroidism.
Thymalin
Тималин
Thymalin is a polypeptide complex extracted from the thymus gland of young calves. It is a potent immunomodulator used clinically to restore and enhance cellular immunity, particularly in individuals with compromised immune systems. The thymus gland is critical for T-lymphocyte maturation, and Thymalin supports this process by stimulating T-cell differentiation, increasing natural killer (NK) cell activity, and normalizing the T-helper/T-suppressor ratio. It has been used for over four decades in Russia with an excellent safety profile. Thymalin is beneficial for acute and chronic infections, post-radiation recovery, cancer adjuvant therapy, and general immune optimization. Its efficacy is dependent on adequate zinc levels in the body.
Vladonix
Владоникс
Vladonix is a natural peptide bioregulator extracted from the thymus gland of young animals, representing the oral equivalent of Thymalin (the injectable form). It contains peptide complex A-6, which supports the thymus gland's function as the "master regulator" of cellular immunity. Vladonix stimulates T-lymphocyte production, normalizes cellular immunity parameters, boosts protein synthesis in immune cells, and has been shown to have oncoprotective (cancer-preventive) properties. It is particularly beneficial for individuals recovering from chemotherapy, radiation, viral infections, or those with autoimmune diseases. Vladonix is suitable for long-term use as part of a comprehensive immune support protocol, with intensive and maintenance phases.
Crystagen
Кристаген
Crystagen is a synthetic tripeptide bioregulator composed of Proline, Glutamic Acid, and Aspartic Acid (Pro-Glu-Asp), specifically designed for rapid immune system correction and enhancement. It acts at the genetic level to stimulate thymus gland function and accelerate T-cell proliferation, making it particularly effective for acute infections and pre-surgical immune preparation. Crystagen has been studied for its ability to quickly restore immune competence in states of immunosuppression, whether from illness, stress, or medical treatments. Its fast-acting mechanism makes it a first-line choice for seasonal flu prevention and rapid immune boost protocols. The tripeptide structure ensures efficient cellular uptake and immediate biological activity.
Ventfort
Вентфорт
Ventfort is a natural peptide bioregulator containing peptide complex A-3, extracted from the blood vessels (specifically the aorta) of young animals. It is designed to strengthen the vascular wall, restore elasticity of endothelial cells, and support overall cardiovascular health. Ventfort regulates lipid metabolism, helps reduce atherosclerotic plaques, normalizes blood pressure, and improves microcirculation throughout the body. Clinical studies in patients with atherosclerosis have shown significant improvements in vascular function and reduction in inflammatory markers. Ventfort is considered suitable for long-term use as part of a comprehensive cardiovascular health protocol.
Vesugen
Везуген
Vesugen is a synthetic tripeptide bioregulator composed of Lysine, Glutamic Acid, and Aspartic Acid (Lys-Glu-Asp), designed to support comprehensive vascular health and circulatory function. It works by regulating metabolism in endothelial cells that line blood vessels, improving microcirculation, reducing vascular permeability, and supporting overall cardiovascular integrity. Vesugen has been studied for its ability to prevent and treat early-stage atherosclerosis, improve blood flow to organs and tissues, and support heart health. Its mechanism involves modulating gene expression in vascular tissue to enhance protein synthesis and cellular repair. The peptide is particularly beneficial for individuals with circulatory disorders, hypertension, or those at risk for cardiovascular disease.
Retinalamin
Ретиналамин
Retinalamin is a peptide-based medication derived from animal retinal tissue (calves). It represents a breakthrough in treating degenerative eye diseases, particularly those affecting the retina. Retinalamin stimulates photoreceptor regeneration, improves metabolism in the retinal pigment epithelium (RPE), enhances microcirculation in retinal blood vessels, and has been shown to restore visual acuity, expand visual fields, and slow the progression of retinal degeneration. It is used extensively in Russia for glaucoma, macular degeneration, diabetic retinopathy, and post-traumatic retinal dystrophies. The medication must be administered via injection—either parabulbar (near the eye) or intramuscularly.
Visoluten
Визолутен
Natural peptide complex from eye tissues. Oral support for vision.
Svetinorm
Светинорм
Natural peptide complex from the liver.
Suprefort
Супрефорт
Suprefort is a natural peptide complex extracted from the pancreas of young animals, designed to support pancreatic function, metabolic regulation, and insulin sensitivity. It has tissue-specific action on pancreatic cells, supporting both endocrine function (insulin production) and exocrine function (digestive enzyme secretion). Suprefort has been clinically studied in patients with Type 2 diabetes mellitus and chronic pancreatitis, showing improvements in blood glucose control, insulin sensitivity, and pancreatic enzyme output. It works by restoring protein synthesis in pancreatic cells, enhancing cellular regeneration, and optimizing metabolic processes. Suprefort is used as an adjunct to conventional treatments for diabetes and pancreatic disorders.
Ovagen
Оваген
Ovagen is a synthetic peptide bioregulator specifically designed to support liver health and gastrointestinal function. It works by regulating metabolic processes in hepatocytes (liver cells), enhancing detoxification pathways, and improving bile secretion for optimal digestion. Ovagen has been studied for its hepatoprotective effects in conditions such as hepatitis, fatty liver disease, and liver damage from medications or alcohol. Additionally, it supports skin health through improved liver detoxification, as many dermatological conditions are linked to impaired hepatic function. The peptide complex is particularly useful during antibiotic recovery and for individuals with chronic liver stress.
Zhenoluten
Женолутен
Zhenoluten is a natural peptide bioregulator extracted from the ovaries of young animals, containing peptide complex A-15 that supports comprehensive female reproductive health. It normalizes ovarian function by regulating protein synthesis in ovarian cells, restoring hormonal balance (particularly estrogen and progesterone), regulating menstrual cycles, and supporting fertility. Zhenoluten has been extensively studied for menopausal symptoms, with clinical evidence showing reduction in hot flashes, night sweats, vaginal dryness, mood swings, and irregular cycles. It delays ovarian aging, extends fertile years, and supports overall women's health across the lifespan. The bioregulator is essential for women experiencing perimenopause, menopause, infertility, or hormonal imbalances.
Libidon
Либидон
Natural peptide complex from the prostate gland. Essential for male health.
Testoluten
Тестолутен
Testoluten is a natural peptide complex extracted from the testes of young animals, containing peptide complex A-13 that supports male reproductive health and testosterone production. It works by normalizing testicular function, stimulating testosterone production via Leydig cell activation, improving spermatogenesis (sperm production and quality), and supporting overall male vitality. Testoluten has been clinically studied for low testosterone (hypogonadism), male infertility (low sperm count and motility), and age-related decline in reproductive function. It helps restore erectile function, enhances libido, improves physical performance, and supports prostate health. Testoluten is recommended for men experiencing andropause, fertility issues, or hormonal decline.
Sigumir
Сигумир
Natural peptide complex from cartilage and bone tissue.
Cartalax
Карталакс
Cartalax is a synthetic tripeptide bioregulator composed of Alanine, Glutamic Acid, and Aspartic Acid (Ala-Glu-Asp), specifically formulated to support cartilage health and joint function. It works by normalizing metabolism in chondrocytes (cartilage cells) and stimulating collagen synthesis, the primary structural protein in cartilage tissue. Cartalax has been studied for its regenerative effects on damaged cartilage, making it valuable for joint injuries, osteoarthritis, and osteochondrosis. The peptide enhances nutrient delivery to cartilage, supports synovial fluid production, and reduces inflammation in joint spaces. Its mechanism involves activating genes responsible for cartilage repair and maintenance, offering a therapeutic approach to joint degeneration.
Chitomur
Читомур
Natural peptide complex from the bladder wall.
Pielotax
Пиелотакс
Natural peptide complex from kidneys.
Prostatilen
Простатилен
Prostatilen is an injectable pharmaceutical peptide bioregulator extracted from prostate tissue. It is the original pharmaceutical form used in Russian clinics for over 30 years. Prostatilen exerts an organotropic (tissue-specific) action on the prostate gland, reducing inflammation, improving microcirculation in prostatic tissue, and normalizing secretory function. It has been extensively studied for chronic prostatitis and benign prostatic hyperplasia (BPH), with clinical trials demonstrating significant improvements in urination, reduction in prostate inflammation, and enhanced sexual function. Prostatilen is available in two forms: intramuscular injection (5-10mg ampules) and rectal suppositories (30-50mg).
Samprost
Сампрост
Injectable pharmaceutical for bladder disorders.
Stamakort
Стамакорт
Natural peptide complex from stomach tissue.
Chelohart
Челохарт
Chelohart is a natural peptide bioregulator extracted from cardiac (heart) tissue of young animals, containing peptide complex A-14 that supports comprehensive cardiovascular health. It works by regulating myocardial metabolism, improving the energy efficiency of heart muscle cells, and enhancing cardiac contractility. Chelohart has been extensively studied for its cardioprotective effects, particularly in individuals recovering from myocardial infarction (heart attack), suffering from heart failure, or dealing with cardiomyopathy. The peptide complex improves oxygen utilization in heart tissue, reduces oxidative stress, supports mitochondrial function, and promotes repair of damaged cardiac cells. It is considered essential for maintaining heart health, especially in individuals with cardiovascular disease or those at risk.
Glandokort
Гландокорт
Glandokort is a natural peptide bioregulator extracted from the adrenal glands of young animals, designed to normalize adrenal function and support the body in managing stress. The adrenal glands produce critical hormones including cortisol, which regulates stress, metabolism, and immune function. Glandokort works by restoring healthy cortisol secretion patterns, preventing adrenal exhaustion, and improving energy levels in individuals experiencing chronic stress or adrenal fatigue. It has been studied for its ability to reduce symptoms of burnout, improve resilience to stress, and support recovery from prolonged physical or emotional strain. The peptide complex helps normalize the hypothalamic-pituitary-adrenal (HPA) axis, which is often dysregulated in chronic stress conditions. Glandokort is essential for maintaining hormonal balance and vitality in high-stress situations.
Gotratix
Готратикс
Gotratix is a natural peptide bioregulator extracted from muscle tissue of young animals, specifically formulated to support skeletal muscle health, enhance protein synthesis, and improve athletic performance. It works by stimulating muscle cells (myocytes) to increase protein production, accelerate tissue repair, and optimize energy metabolism within muscle fibers. Gotratix has been studied for its ability to prevent and reverse muscle atrophy (muscle wasting), enhance strength and endurance, and speed recovery from muscle injuries or intense physical training. The peptide complex is particularly valuable for athletes, elderly individuals experiencing sarcopenia (age-related muscle loss), and patients recovering from prolonged immobilization or muscle-wasting diseases. Gotratix supports the maintenance of lean muscle mass and overall physical vitality.
Taxorest
Таксорест
Natural peptide complex from lung tissue.
Bonomarlot
Бономарлот
Bonomarlot is a natural peptide bioregulator extracted from bone marrow tissue of young animals, containing tissue-specific peptides that support hematopoiesis (blood cell formation) and immune function. It works by stimulating stem cells in the bone marrow to differentiate into red blood cells, white blood cells, and platelets, making it invaluable for treating anemia, immunodeficiency, and post-chemotherapy recovery. Bonomarlot has been extensively studied for its ability to restore normal blood counts after radiation therapy or chemotherapy, enhance immune cell production, and support overall bone marrow health. The peptide complex regulates the bone marrow microenvironment, promoting healthy cell proliferation and maturation. It is particularly beneficial for individuals with compromised blood production or immune function.
Bonothyrk
Бонотирк
Bonothyrk is a natural peptide bioregulator extracted from the parathyroid glands of young animals, designed to regulate calcium metabolism and support bone health. The parathyroid glands produce parathyroid hormone (PTH), which is critical for maintaining proper calcium and phosphorus balance in the body. Bonothyrk works by normalizing parathyroid function, helping to regulate calcium levels in the blood, improve bone mineral density, and support skeletal integrity. It has been studied for its therapeutic effects in osteoporosis, hyperparathyroidism, and calcium metabolism disorders. The peptide complex enhances calcium absorption, reduces excessive bone resorption, and supports the formation of new bone tissue. Bonothyrk is particularly valuable for individuals with bone density issues or imbalances in calcium homeostasis.
Vilon
Вилон
Vilon is a synthetic dipeptide bioregulator composed of Lysine and Glutamic Acid (Lys-Glu), designed to optimize thymus function and cellular immunity. As a short-chain peptide, it penetrates cellular membranes to directly interact with DNA, activating genes responsible for T-lymphocyte differentiation and maturation. Vilon has been extensively studied for its rapid immune-enhancing effects, particularly in immunocompromised states and autoimmune conditions. It modulates cytokine production, reduces systemic inflammation, and has shown promise in cancer adjuvant therapy by supporting immune surveillance. The dipeptide structure allows for quick absorption and immediate biological activity, making it ideal for acute immune challenges.
Chonluten
Хонлутен
Synthesized peptide complex for respiratory system.
Kartalax
Карталакс
Synthesized peptide (Ala-Glu-Asp) for cartilage and joints.
Bronchogen
Бронхоген
Bronchogen is a synthetic peptide bioregulator specifically designed to support bronchial health and respiratory function. As a Generation 2 Cytogen, it contains a short-chain peptide sequence that targets the bronchial mucosa, the tissue lining the airways that carries air to and from the lungs. Bronchogen has been extensively studied for its ability to restore the structural integrity of bronchial tissue, reduce chronic inflammation in the airways, and improve overall respiratory function. Clinical trials have demonstrated significant improvements in lung function parameters (FEV1, FVC), reduction in exacerbations, and enhanced quality of life in patients with chronic obstructive pulmonary disease (COPD), chronic bronchitis, and asthma. The peptide works at the cellular level to normalize metabolic processes in bronchial cells, enhance mucociliary clearance (the lungs natural cleaning mechanism), and reduce the inflammatory cascade that damages airways over time. Bronchogen is particularly valuable for individuals with chronic respiratory conditions, smokers recovering from lung damage, and those exposed to environmental pollutants or occupational respiratory hazards.
Pancragen
Панкраген
Synthesized peptide for pancreatic function.
Testagen
Тестаген
Synthesized peptide for male reproductive health.
Normoftal
Нормофтал
Synthesized peptide for comprehensive eye health.
Livagen
Ливаген
Synthesized peptide for liver protection and regeneration.
Honluten
Хонлутен
Synthesized peptide for lung tissue repair.
Cardiogen
Кардиоген
Cardiogen is a synthetic tetrapeptide bioregulator designed to optimize myocardial (heart muscle) metabolism and enhance cardiac function. It works by regulating energy production in cardiomyocytes (heart muscle cells), improving contractility, and supporting overall cardiovascular performance. Cardiogen has been extensively studied in patients with coronary heart disease, chronic heart failure, and post-myocardial infarction recovery, showing significant improvements in left ventricular ejection fraction (LVEF), exercise tolerance, and quality of life. The peptide enhances oxygen utilization in cardiac tissue, reduces arrhythmias, and supports the repair of damaged myocardium. It is particularly valuable as an adjunct therapy for individuals with compromised heart function.
GPL Man
GPL Man
GPL® Man is a comprehensive peptide complex designed specifically for men's health and anti-aging. It combines peptide extracts from the pancreas, blood vessels, brain, liver, pineal gland, and testicles. This multi-targeted approach addresses the key systems involved in male aging, supporting hormonal balance, vascular health, cognitive function, and detoxification.
GPL Femme
GPL Femme
GPL® Femme is an innovative peptide complex designed to slow down aging processes in women. It contains peptide extracts from the thyroid gland, blood vessels, brain, liver, and pineal gland. This formulation targets the neuroendocrine and vascular systems to support hormonal balance, skin health, metabolism, and overall well-being.