The Khavinson Catalog21+ Bioregulators
The complete inventory of original Russian peptide bioregulators. Filter by body system, type, or health goal.
Cortexin
Кортексин
Cortexin is a complex of water-soluble polypeptide fractions extracted from the cerebral cortex of young cattle, with molecular weights ranging from 1,000 to 10,000 Daltons. These low-molecular-weight neuropeptides are capable of crossing the blood-brain barrier and exerting tissue-specific effects on the cerebral cortex. The peptide complex modulates neuronal metabolism, regulates neurotransmitter balance (particularly serotonin, dopamine, and amino acids), and restores bioelectrical activity in the brain. Cortexin is a prescription injectable medicine in Russia and is not sold as a supplement.
Cerluten
Церлутен
Cerluten is a natural peptide bioregulator extracted from the cerebral cortex of young animals, containing tissue-specific, low-molecular-weight peptides that support comprehensive brain and central nervous system function. Once absorbed, these peptides interact with specific regions of neuronal DNA, acting as epigenetic switches that activate genes responsible for brain repair, protein synthesis, and cellular regeneration. Cerluten enhances metabolic efficiency within brain tissue, provides antioxidant protection against oxidative damage (particularly critical for the brain), regulates peroxide oxidation, and supports microcirculation to ensure neurons receive adequate oxygen and nutrients. It has been shown to improve synaptic plasticity, neurotransmitter regulation, and overall CNS resilience.
Pinealon
Пинеалон
Pinealon is a synthetic tripeptide bioregulator composed of Glutamic Acid, Aspartic Acid, and Arginine (Glu-Asp-Arg), also known as EDR peptide. Originally studied in Russia and derived from or inspired by pineal gland tissue extracts, Pinealon is designed to optimize pineal gland and overall brain function. Due to its small molecular size, it penetrates cellular and nuclear membranes to directly interact with DNA, modulating gene expression and protein synthesis in neurons. It enhances pineal gland activity (including melatonin production), optimizes neurotransmitter function (serotonin, dopamine, GABA, acetylcholine), provides comprehensive neuroprotection by reducing oxidative stress and supporting mitochondrial function, and influences the MAPK/ERK signaling pathway. Pinealon is recognized as a powerful nootropic with applications in cognitive enhancement and age-related neuroprotection.
Epithalamin
Эпиталамин
Epithalamin is a natural polypeptide extract from the bovine pineal gland, representing the "Gold Standard" of Khavinson bioregulators. It regulates the entire neuroendocrine system and has been studied in research on aging. Studies from the originating group describe effects on melatonin secretion and on telomerase in cell models. Animal studies from the originating group reported longer life span in fruit flies, mice and rats, and Russian long-term studies in elderly people used it as an injection; none of this tested an oral supplement. Epithalamin works by restoring the function of the pineal gland, which acts as the body's biological clock and regulates circadian rhythms, reproductive aging, and systemic homeostasis.
Endoluten
Эндолутен
Endoluten is a natural peptide bioregulator extracted from the pineal gland of young animals, representing the oral equivalent of Epithalamin (the injectable gold standard). It contains peptide complex A-8, consisting of low-molecular-weight peptides with tissue-specific action on the pineal gland. Endoluten works by supporting the pineal gland's natural production of melatonin and other regulatory hormones, rather than supplying melatonin exogenously. It normalizes all cyclic processes in the body—including sleep-wake cycles, hormonal balance, reproductive function, and immune regulation. Due to its potency, Endoluten is typically taken less frequently than other bioregulators (e.g., every 3 days). Russian literature discusses it in the context of systemic bioregulation and aging research. PubMed lists no studies under the Endoluten name.
Epitalon
Эпиталон
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) that is the active component of Epithalamin, confirmed to exist endogenously in pineal gland extracts in 2017. It is the most researched synthetic anti-aging peptide in the world. Epitalon activates the telomerase enzyme by inducing expression of TERT gene components, leading to telomere elongation at the ends of chromosomes—the protective caps that shorten with each cell division and contribute to cellular aging. These telomere findings come from cell cultures (PMID 12937682); they have not been shown in people. Epitalon has also been studied in research on melatonin regulation and antioxidant activity. Regulatory context: on July 24, 2026 an FDA advisory committee (the Pharmacy Compounding Advisory Committee) voted narrowly, against the FDA staff recommendation, to recommend adding epitalon to the 503A bulks list used by compounding pharmacies. The vote is non-binding, and FDA had not acted on it as of October 2026. Epitalon is not an FDA-approved drug.
Thyreogen
Тиреоген
Natural peptide complex from the thyroid gland. Traditionally used to support normal thyroid function.
Thymalin
Тималин
Thymalin is a polypeptide complex extracted from the thymus gland of young calves. It is a potent immunomodulator used clinically to restore and enhance cellular immunity, particularly in individuals with compromised immune systems. The thymus gland is critical for T-lymphocyte maturation, and Thymalin supports this process by stimulating T-cell differentiation, increasing natural killer (NK) cell activity, and normalizing the T-helper/T-suppressor ratio. It has been used for over four decades in Russia with an excellent safety profile. Russian clinical literature reports its use as an injectable immunomodulator in a range of clinical settings. Its efficacy is dependent on adequate zinc levels in the body.
Vladonix
Владоникс
Vladonix is a natural peptide bioregulator extracted from the thymus gland of young animals, representing the oral equivalent of Thymalin (the injectable form). It contains peptide complex A-6, which supports the thymus gland's function as the "master regulator" of cellular immunity. Vladonix stimulates T-lymphocyte production, normalizes cellular immunity parameters, boosts protein synthesis in immune cells, and has been examined in Russian research on age-related immune changes. The human data people cite come from the injectable extract Thymalin, which do not automatically apply to oral capsules. Vladonix is suitable for long-term use as part of a comprehensive immune support protocol, with intensive and maintenance phases.
Crystagen
Кристаген
Crystagen is a synthetic tripeptide bioregulator composed of Proline, Glutamic Acid, and Aspartic Acid (Pro-Glu-Asp), traditionally used to support normal immune function. It has been studied in small Russian reports and cell research on thymus function and T-cell parameters. The tripeptide structure ensures efficient cellular uptake and immediate biological activity.
Ventfort
Вентфорт
Ventfort is a natural peptide bioregulator containing peptide complex A-3, extracted from the blood vessels (specifically the aorta) of young animals. It is designed to strengthen the vascular wall, restore elasticity of endothelial cells, and support overall cardiovascular health. Brand literature describes support for normal vascular tone and microcirculation. Published human evidence for the oral product is limited. Ventfort is considered suitable for long-term use as part of a comprehensive cardiovascular health protocol.
Vesugen
Везуген
Vesugen is a synthetic tripeptide bioregulator composed of Lysine, Glutamic Acid, and Aspartic Acid (Lys-Glu-Asp), designed to support comprehensive vascular health and circulatory function. It works by regulating metabolism in endothelial cells that line blood vessels, improving microcirculation, reducing vascular permeability, and supporting overall cardiovascular integrity. Vesugen has been studied in small Russian reports and cell research on vascular tissue. Its mechanism involves modulating gene expression in vascular tissue to enhance protein synthesis and cellular repair.
Retinalamin
Ретиналамин
Retinalamin is a peptide-based medication derived from animal retinal tissue (calves). It has been studied in Russia in degenerative eye conditions, particularly those affecting the retina. Retinalamin stimulates photoreceptor regeneration, improves metabolism in the retinal pigment epithelium (RPE), enhances microcirculation in retinal blood vessels, according to Russian clinical literature. It is a prescription medicine in Russia and is not sold as a supplement. The medication must be administered via injection—either parabulbar (near the eye) or intramuscularly.
Visoluten
Визолутен
Natural peptide complex from eye tissues. Oral support for vision.
Svetinorm
Светинорм
Natural peptide complex from the liver.
Suprefort
Супрефорт
Suprefort is a natural peptide complex extracted from the pancreas of young animals, designed to support normal pancreatic function. It has tissue-specific action on pancreatic cells, supporting both endocrine function (insulin production) and exocrine function (digestive enzyme secretion). Brand literature describes support for protein synthesis in pancreatic cells. Published human evidence for the oral product is limited.
Ovagen
Оваген
Ovagen is a synthetic peptide bioregulator specifically designed to support liver health and gastrointestinal function. It works by regulating metabolic processes in hepatocytes (liver cells), enhancing detoxification pathways, and improving bile secretion for optimal digestion. Ovagen has been studied in cell and animal research on liver cells. Published human evidence for the oral product is limited.
Zhenoluten
Женолутен
Zhenoluten is a natural peptide bioregulator extracted from the ovaries of young animals, containing peptide complex A-15 that supports comprehensive female reproductive health. It normalizes ovarian function by regulating protein synthesis in ovarian cells, according to brand literature. Published human evidence for the oral product is limited. The label lists pregnancy and lactation as contraindications.
Libidon
Либидон
Natural peptide complex from the prostate gland. Traditionally used to support normal prostate function.
Testoluten
Тестолутен
Testoluten is a natural peptide complex extracted from the testes of young animals, containing peptide complex A-13 that is traditionally used to support normal testicular function and male reproductive wellness. Published human evidence for the oral product is limited.
Sigumir
Сигумир
Natural peptide complex from cartilage and bone tissue.
Cartalax
Карталакс
Cartalax is a synthetic tripeptide bioregulator composed of Alanine, Glutamic Acid, and Aspartic Acid (Ala-Glu-Asp), specifically formulated to support cartilage health and joint function. It works by normalizing metabolism in chondrocytes (cartilage cells) and stimulating collagen synthesis, the primary structural protein in cartilage tissue. Cartalax has been studied in cell research on cartilage cells. Published human evidence for the oral product is limited.
Chitomur
Читомур
Natural peptide complex from the bladder wall.
Pielotax
Пиелотакс
Natural peptide complex from kidneys.
Prostatilen
Простатилен
Prostatilen is an injectable pharmaceutical peptide bioregulator extracted from prostate tissue. It is the original pharmaceutical form used in Russian clinics for over 30 years. Prostatilen exerts an organotropic (tissue-specific) action on the prostate gland, according to Russian pharmacological literature. It has been studied in Russian prostate research as a prescription medicine. Prostatilen is available in two forms: intramuscular injection (5-10mg ampules) and rectal suppositories (30-50mg).
Samprost
Сампрост
Russian injectable pharmaceutical studied in bladder research.
Stamakort
Стамакорт
Natural peptide complex from stomach tissue.
Chelohart
Челохарт
Chelohart is a natural peptide bioregulator extracted from cardiac (heart) tissue of young animals, containing peptide complex A-14 that supports comprehensive cardiovascular health. It works by regulating myocardial metabolism, improving the energy efficiency of heart muscle cells, and enhancing cardiac contractility. Published human evidence for the oral product is limited.
Glandokort
Гландокорт
Glandokort is a natural peptide bioregulator extracted from the adrenal glands of young animals, designed to normalize adrenal function and support the body in managing stress. The adrenal glands produce critical hormones including cortisol, which regulates stress, metabolism, and immune function. Brand literature describes support for normal adrenal function and stress resilience; published human evidence for the oral product is limited. The peptide complex helps normalize the hypothalamic-pituitary-adrenal (HPA) axis, which is often dysregulated in chronic stress conditions. Glandokort is essential for maintaining hormonal balance and vitality in high-stress situations.
Gotratix
Готратикс
Gotratix is a natural peptide bioregulator extracted from muscle tissue of young animals, specifically formulated to support skeletal muscle health, enhance protein synthesis, and improve athletic performance. It works by stimulating muscle cells (myocytes) to increase protein production, accelerate tissue repair, and optimize energy metabolism within muscle fibers. Brand literature describes support for normal muscle function and recovery after training; published human evidence for the oral product is limited. Gotratix supports the maintenance of lean muscle mass and overall physical vitality.
Taxorest
Таксорест
Natural peptide complex from lung tissue.
Bonomarlot
Бономарлот
Bonomarlot is a natural peptide bioregulator extracted from bone marrow tissue of young animals, containing tissue-specific peptides that support hematopoiesis (blood cell formation) and immune function. It works by stimulating stem cells in the bone marrow to differentiate into red blood cells, white blood cells, and platelets, according to brand literature. Published human evidence for the oral product is limited. The peptide complex regulates the bone marrow microenvironment, promoting healthy cell proliferation and maturation.
Bonothyrk
Бонотирк
Bonothyrk is a natural peptide bioregulator extracted from the parathyroid glands of young animals, designed to regulate calcium metabolism and support bone health. The parathyroid glands produce parathyroid hormone (PTH), which is critical for maintaining proper calcium and phosphorus balance in the body. Bonothyrk works by normalizing parathyroid function, helping to regulate calcium levels in the blood, improve bone mineral density, and support skeletal integrity. Published human evidence for the oral product is limited.
Vilon
Вилон
Vilon is a synthetic dipeptide bioregulator composed of Lysine and Glutamic Acid (Lys-Glu), designed to optimize thymus function and cellular immunity. As a short-chain peptide, it penetrates cellular membranes to directly interact with DNA, activating genes responsible for T-lymphocyte differentiation and maturation. Vilon has been studied in cell and animal research on immune cells. The dipeptide structure allows for quick absorption and immediate biological activity, making it ideal for acute immune challenges.
Chonluten
Хонлутен
Synthesized peptide complex for respiratory system.
Bronchogen
Бронхоген
Bronchogen is a synthetic peptide bioregulator specifically designed to support bronchial health and respiratory function. As a Generation 2 Cytogen, it contains a short-chain peptide sequence that targets the bronchial mucosa, the tissue lining the airways that carries air to and from the lungs. Bronchogen has been studied in research on bronchial tissue. Most published data come from Russian cell and animal studies. The peptide works at the cellular level to normalize metabolic processes in bronchial cells, enhance mucociliary clearance (the lungs natural cleaning mechanism), and reduce the inflammatory cascade that damages airways over time.
Pancragen
Панкраген
Synthesized peptide for pancreatic function.
Testagen
Тестаген
Synthesized peptide for male reproductive health.
Normoftal
Нормофтал
Synthesized peptide for comprehensive eye health.
Livagen
Ливаген
Synthesized peptide traditionally used to support normal liver function.
Cardiogen
Кардиоген
Cardiogen is a synthetic tetrapeptide bioregulator designed to optimize myocardial (heart muscle) metabolism and enhance cardiac function. It works by regulating energy production in cardiomyocytes (heart muscle cells), improving contractility, and supporting overall cardiovascular performance. Most published data come from cell research. Published human evidence for oral use is limited.
GPL Man
GPL Man
GPL® Man is a comprehensive peptide complex designed specifically for men's health and anti-aging. It combines peptide extracts from the pancreas, blood vessels, brain, liver, pineal gland, and testicles. This multi-targeted approach addresses the key systems involved in male aging, supporting hormonal balance, vascular health, cognitive function, and detoxification.
GPL Femme
GPL Femme
GPL® Femme is an innovative peptide complex designed to slow down aging processes in women. It contains peptide extracts from the thyroid gland, blood vessels, brain, liver, and pineal gland. This formulation targets the neuroendocrine and vascular systems to support hormonal balance, skin health, metabolism, and overall well-being.