Health hubs · Gut & digestive health

Gut and digestive health: stomach, liver and pancreas bioregulators and what the evidence shows

Ongoing indigestion, bloating or bowel changes deserve a proper workup before any supplement. Guidelines call for testing for H. pylori, endoscopy for new indigestion from age 60, and celiac testing when IBS comes with diarrhea, because these find treatable causes. Digestive bioregulators (stomach, gastric-mucin, liver, bile and pancreas peptides) have only animal and lab research behind them, on different preparations. No human trial has tested any of the capsules.

Written by The Bioregulator Atlas editorial team · Medical review pending · Facts and prices checked Oct 7, 2026

Indigestion, age ≥60: ACG/CAG suggest endoscopy; under 60, test for H. pylori and treat if positive(source)
IBS: ACG 2021: celiac serology with diarrhea symptoms; a limited low-FODMAP trial(source)
Digestive bioregulators: Animal and lab studies only (e.g. Ventvil/Livagen liver review); no human trials of capsules(source)
Capsules: Stomek, Gastrogen, Liverra $67.50 / 30 caps; Vita Detox $144.50 / 30 caps (Vita-Stream, Oct 6, 2026)

Human studies and guidelines: get the basics checked

The 2017 ACG/CAG dyspepsia guideline suggests that people aged 60 or older with new indigestion have an upper endoscopy, and that younger people have a non-invasive H. pylori test and treatment if it is positive, then a trial of acid-reducing medicine if needed. These steps find and treat ulcers, infection and, rarely, cancer.

The 2021 ACG IBS guideline suggests blood tests for celiac disease and a fecal calprotectin test (to look for inflammatory bowel disease) in people with IBS and diarrhea, and recommends a limited trial of a low-FODMAP diet for overall IBS symptoms. Gut-directed psychotherapy also has evidence.

See a clinician promptly for weight loss you cannot explain, black or bloody stools, trouble swallowing, repeated vomiting or anemia.

Clinical guidelineMoayyedi et al. 2017, Am J Gastroenterol: ACG and CAG clinical guideline on dyspepsia
Clinical guidelineLacy et al. 2021, Am J Gastroenterol: ACG clinical guideline on irritable bowel syndrome

Human studies: digestive bioregulators

We found no human trial of any stomach, gastric-mucin, liver, bile or pancreas bioregulator capsule, including Stomek, Gastrogen, Liverra, Biltorin, Vita Detox, Stamakort, Suprefort, Svetinorm or Ovagen.

Lab and animal studies

The research closest to these products is a 2020 Russian review of the liver polypeptide complex Ventvil and the synthetic tetrapeptide Livagen (Lys-Glu-Asp-Ala). It summarizes animal models of liver injury and cell studies. The authors report protective effects in those models, but these are different preparations from the capsules, and animal results often do not carry over to people.

Animal studyKuznik et al. 2020, Adv Gerontol: liver polypeptide complex and the KEDA tetrapeptide (review of animal and lab work, Russian)

How to choose, if you try one

The Vita house line has single-tissue Stomek (stomach), Gastrogen (gastric mucin), Liverra (liver) and Biltorin (bile), plus Vita Detox, which combines liver, kidney, bile, stomach and gastric-mucin peptides. "Detox" is the label's word: it is not a cleanse or a weight-loss product. GARMONIA's Stamakort (stomach), Suprefort (pancreas) and Svetinorm (liver) are the original Cytomax products.

Use one product for one month and keep a symptom diary. Ask your clinician first if you have a digestive or liver diagnosis or take regular medication, since most drugs are processed by the liver.

Digestive bioregulator capsules (Vita-Stream)

Dietary supplements with structure/function wording. No human trial has tested these products by name. Not for use during pregnancy or lactation (label). Not intended to diagnose, treat, cure or prevent any disease.

StomekVita Peptides house line · stomach
Stomach peptides; the label says it helps maintain normal stomach and gastric-mucosa balance.
30 caps $67.50 · 60 caps $135.00 (Vita-Stream, Oct 6, 2026)
See Stomek at Vita-Stream Paid linkOur profile
GastrogenVita Peptides house line · gastric mucin
Gastric-mucin peptides; labeled for normal gastric mucosa and digestive balance.
30 caps $67.50 · 60 caps $135.00 (Vita-Stream, Oct 6, 2026)
See Gastrogen at Vita-Stream Paid linkOur profile
Vita DetoxVita Peptides house line · liver, kidney, bile, stomach and gastric mucin
Liver, kidney, bile, stomach and gastric-mucin peptides in one capsule; labeled for digestive comfort and metabolic balance.
30 caps $144.50 · 60 caps $289.00 (Vita-Stream, Oct 6, 2026)
See Vita Detox at Vita-Stream Paid linkOur profile
LiverraVita Peptides house line · liver
Liver peptides; labeled for normal metabolic and nutrient balance.
30 caps $67.50 · 60 caps $135.00 (Vita-Stream, Oct 6, 2026)
See Liverra at Vita-Stream Paid linkOur profile
Stamakort (A-10)Sold by Vita-Stream · stomach
The original GARMONIA stomach Cytomax (A-10).
See Stamakort (A-10) at Vita-Stream Paid linkOur profile
Suprefort (A-1)Sold by Vita-Stream · pancreas
GARMONIA pancreas Cytomax (A-1); the Vita house line has no pancreas product.
See Suprefort (A-1) at Vita-Stream Paid linkOur profile

Use code KymataLabs at checkout

FAQ

Do stomach bioregulators help with indigestion?

That has not been tested in people. The research behind digestive bioregulators is animal and lab work on related preparations. Indigestion that keeps coming back should be checked: H. pylori testing, and endoscopy from age 60, find treatable causes.

Is Vita Detox a cleanse?

No. It is a capsule of liver, kidney, bile, stomach and gastric-mucin peptides labeled for digestive comfort and metabolic balance. It is not a cleanse, a laxative or a weight-loss product.

Are there liver bioregulator studies?

There are Russian animal and lab studies of the liver complex Ventvil and the synthetic peptide Livagen, reviewed in 2020. There are no human trials of Liverra, Svetinorm or Ovagen capsules.

Can I take digestive bioregulators with my medications?

There are no interaction studies. Most medicines are processed by the liver, so ask your clinician or pharmacist first.

Do you earn money from these links?

Yes. Vita-Stream links are affiliate links (marked Paid), and orders placed with the code KymataLabs are credited to our affiliate account at no extra cost to you. It does not change the evidence notes.

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Not medical advice. Medical review pending: this page has not yet been reviewed by a licensed clinician. Statements about dietary supplements have not been evaluated by the Food and Drug Administration; these products are not intended to diagnose, treat, cure or prevent any disease. Compounded medicines are not FDA-approved. Prices change often; confirm on the seller's page.