Dopamine Resensitization& Neuro-Drive
A specific protocol for restoring "Tonic" dopamine baseline, upregulating receptor density, and recovering motivation after stimulant use, burnout, or chronic stress.
The "Tonic vs. Phasic" Balance
Modern life (scrolling, stimulants, sugar) constantly spikes our "Phasic" dopamine. The brain compensates by downregulating receptors, leading to a low "Tonic" baseline—the feeling of unmotivation, apathy, and burnout.
The Goal: To stop chasing spikes and instead raise the specific water level of the pool. This protocol uses bioregulators to repair the neural tissue and precursors to support natural synthesis.
📉 Receptor Recovery
Upregulating D2/D3 receptors heavily desensitized by overstimulation.
🏭 Enzyme Support
Boosting Tyrosine Hydroxylase, the rate-limiting enzyme for dopamine creation.
Neural & Adrenal Restoration
Goal: Fix the HPA Axis & Cortex
Burnout isn't just "in your head"—it's physiological. Chronic stress blunts dopamine via cortisol. We must fix the adrenals first.
Cerluten (Brain)
Normalizes the function of the brain cortex. In Russian trials, it demonstrated an ability to improve "psycho-emotional status" and reduce fatigue in patients with cerebrovascular insufficiency.
Glandokort (Adrenal)
The "Burnout Breaker." Regulates the adrenal glands to normalize cortisol secretion. High cortisol directly suppresses dopamine capabilities.
Synthesis & Density
Goal: The "Mr. Happy" Stack Mechanism
Bromantane (Ladasten)
Unique ActoprotectorDeveloped in Russia for cosmonauts. Unlike stimulants that *deplete* dopamine, Bromantane *increases* its synthesis by upregulating the enzyme Tyrosine Hydroxylase.
Uridine + CDP Choline
Receptor DensityUridine Monophosphate enhances the growth of neurites and increases the density of dopamine receptors in the membrane.
The "Nuclear Option"
Goal: Dopaminergic Neuron Regeneration
⚠️ RESEARCH CHEMICAL WARNING
9-Me-BC (9-Methyl-beta-carboline) is a potent research chemical. While it shows incredible promise for regenerating dopaminergic neurons in animal models, human safety data is limited. Photosensitivity is a known side effect. Proceed with extreme caution.
9-Me-BC
Neuro-RegenerativeA beta-carboline that has been shown to induce the growth of dopaminergic neurons in the hippocampus and protect them from toxicity. It is often used by biohackers to "heal" the brain after years of stimulant abuse (Adderall, Meth, etc.).
- • Protocol: 10-15mg daily for 20-30 days max.
- • Precaution: AVOID direct sunlight (UV) during cycle.
- • Precaution: Do NOT mix with methyl-donors (SAMe) or stimulants.
20-Day "Resensitization" Cycle
Cycle Notes:
- Caffeine: Reduce intake by 50% during this cycle to allow adenosine receptors to reset alongside dopamine.
- Stimulants: Cease all stronger dopaminergics (Adderall, Ritalin, Ephedrine) during the 20 days.
- Support: Take Omega-3s and Magnesium Bisglycinate nightly.